Y-chromosome STR haplotypes in Sweden

Gunilla Holmlund; Helena Nilsson; Andreas Karlsson; Bertil Lindblom

doi:10.1016/j.forsciint.2005.05.008

Y-chromosome STR haplotypes in Sweden

Forensic Sci Int. 2006 Jun 27;160(1):66-79. doi: 10.1016/j.forsciint.2005.05.008. Epub 2005 Jun 22.

Authors

Gunilla Holmlund¹, Helena Nilsson, Andreas Karlsson, Bertil Lindblom

Affiliation

¹ The National Board of Forensic Medicine, Department of Forensic Genetics, University Hospital, SE-581 85 Linköping, Sweden. gunilla.holmlund@rmv.se

PMID: 15978763
DOI: 10.1016/j.forsciint.2005.05.008

Abstract

A total of 708 men, with Swedish names, from different parts of Sweden have been typed for the Y-chromosome minimal haplotype STR markers DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393 and DYS385. Of these, 403 men were of geographically undefined Swedish origin and the rest, 305, from seven defined geographical regions. PCR-products were detected by ABI377 using sequenced allelic ladders. An evaluation of the 708 chromosomes revealed 423 different haplotypes. Only 100 of the haplotypes were found more than once. The over all haplotype diversity was 0.994. The haplotype 14, 12, 28, 23, 10, 11, 13, 14-14 has the highest frequency of 5.79% and is significantly Swedish, when compared to other European populations.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromosomes, Human, Y*
DNA Fingerprinting
Genetics, Population*
Haplotypes*
Humans
Male
Polymerase Chain Reaction
Sweden
Tandem Repeat Sequences*