Triterpenoids from Sanguisorba officinalis

Xin Liu; Yanxing Cui; Qiang Yu; Biao Yu

doi:10.1016/j.phytochem.2005.05.011

Triterpenoids from Sanguisorba officinalis

Phytochemistry. 2005 Jul;66(14):1671-9. doi: 10.1016/j.phytochem.2005.05.011.

Authors

Xin Liu¹, Yanxing Cui, Qiang Yu, Biao Yu

Affiliation

¹ State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, PR China.

PMID: 15979111
DOI: 10.1016/j.phytochem.2005.05.011

Abstract

Seven triterpenoids, i.e., 3beta-[(alpha-L-arabinopyranosyl)oxy]-19beta-hydroxyurs-12,20(30)-dien-28-oic acid (1), 3beta-[(alpha-L-arabinopyranosyl)oxy]-urs-11,13(18)-dien-28-oic acid beta-D-glucopyranosyl ester (2), 2alpha,3alpha,23-trihydroxyurs-12-en-24,28-dioic acid 28-beta-D-glucopyranosyl ester (3), 3beta-[(alpha-L-arabinopyranosyl)oxy]-urs-12,19(20)-dien-28-oic acid (4), 3beta-[(alpha-L-arabinopyranosyl)oxy]-urs-12,19(29)-dien-28-oic acid (5), 3beta-[(alpha-L-arabinopyranosyl)oxy]-19alpha-hydroxyolean-12-en-28-oic acid (6), 2alpha,3beta-dihydroxy-28-norurs-12,17,19(20),21-tetraen-23-oic cid (7), together with three known ones (8-10), were isolated from the roots of Sanguisorba officinalis. Their structures were determined by spectroscopic and chemical methods. Compounds 7 and 10 showed marginal inhibition activity against the growth of tumor cell lines.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents, Phytogenic / chemistry
Antineoplastic Agents, Phytogenic / isolation & purification
Antineoplastic Agents, Phytogenic / pharmacology
Cell Line, Tumor
Humans
Molecular Structure
Plant Roots / chemistry
Sanguisorba / chemistry*
Triterpenes / chemistry*
Triterpenes / isolation & purification
Triterpenes / pharmacology

Substances

Antineoplastic Agents, Phytogenic
Triterpenes