Abstract
Natural eCG consists of as much as 45% carbohydrate side chains. The present paper deals with the analysis of the roles of the N- and O-linked saccharides of this hormone in the different steps of its activity and its possible replacement by recombinant eCG expressed in baculovirus-insect cell systems.
MeSH terms
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Animals
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Baculoviridae
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Biological Assay
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Cell Line
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Female
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Glycoside Hydrolases / genetics
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Glycosyltransferases / genetics
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Gonadotropins, Equine / chemistry
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Gonadotropins, Equine / metabolism
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Gonadotropins, Equine / physiology*
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Horses
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Insecta
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Male
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Oligosaccharides / metabolism*
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Recombinant Proteins / genetics
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Recombinant Proteins / metabolism
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Spodoptera
Substances
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Gonadotropins, Equine
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Oligosaccharides
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Recombinant Proteins
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Glycosyltransferases
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Glycoside Hydrolases