[Conjunctival blistering associated with pemphigus vulgaris: report of a case]

Abstract

Clinical case: A patient with a conjunctival blister was diagnosed with pemphigus vulgaris by immunofluorescence tests performed on a conjunctival biopsy.

Discussion: Pemphigus vulgaris is an uncommon but serious autoimmune disease that produces blisters of the skin and mucous membranes. Ocular findings are rare, but include conjunctivitis and marginal eyelid erosions. Conjunctival blisters and erosions related to this condition have not been previously reported in the literature. This diagnosis can be made through direct immunofluorescence tests performed on biopsy samples of affected tissue. Unless the condition is properly diagnosed and treated, it has a high mortality.