Imaging in breast cancer: Magnetic resonance spectroscopy

Breast Cancer Res. 2005;7(4):149-52. doi: 10.1186/bcr1202. Epub 2005 May 12.


A technique called in vivo magnetic resonance spectroscopy (MRS) can be performed along with magnetic resonance imaging (MRI) to obtain information about the chemical content of breast lesions. This information can be used for several clinical applications, such as monitoring the response to cancer therapies and improving the accuracy of lesion diagnosis. Initial MRS studies of breast cancer show promising results, and a growing number of research groups are incorporating the technique into their breast MRI protocols. This article introduces 1H-MRS of the breast, reviews the literature, discusses current methods and technical issues, and describes applications for treatment monitoring and lesion diagnosis.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Breast Neoplasms / chemistry*
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / therapy
  • Diagnosis, Differential
  • Female
  • Humans
  • Magnetic Resonance Spectroscopy* / methods
  • Protons
  • Sensitivity and Specificity
  • Treatment Outcome


  • Protons