Signaling to cytoskeletal dynamics during chemotaxis

Markus Affolter; Cornelis J Weijer

doi:10.1016/j.devcel.2005.06.003

Signaling to cytoskeletal dynamics during chemotaxis

Dev Cell. 2005 Jul;9(1):19-34. doi: 10.1016/j.devcel.2005.06.003.

Authors

Markus Affolter¹, Cornelis J Weijer

Affiliation

¹ Department of Cell Biology, Biozentrum University of Basel, Klingelbergstr. 70, CH-4056 Basel, Switzerland.

PMID: 15992538
DOI: 10.1016/j.devcel.2005.06.003

Abstract

We review insights in signaling pathways controlling cell polarization and cytoskeletal organization during chemotactic movement in Dictyostelium amoebae and neutrophils. We compare and contrast these insights with our current understanding of pathways controlling chemotactic movements in more-complex multicellular developmental contexts.

Publication types

Review

MeSH terms

Actins / physiology
Animals
Cell Polarity
Chemotaxis / physiology*
Cytoskeleton / physiology*
Dictyostelium / physiology
Drosophila / physiology
Gastrula / physiology
Myosins / physiology
Neutrophils / physiology
Receptor Protein-Tyrosine Kinases / physiology
Signal Transduction*
Vertebrates / embryology
Vertebrates / physiology

Substances

Actins
Receptor Protein-Tyrosine Kinases
Myosins