Genetic sperm defects

Theriogenology. 2005 Aug;64(3):457-68. doi: 10.1016/j.theriogenology.2005.05.005.


Genetic sperm defects are specific sperm defects, which have been shown to have a genetic mode of transmission. Such genetic linkage, either direct or indirect, has been associated with a number of sperm defects in different species, with this number increasing with improved diagnostic capabilities. A number of sperm defects, which have proven or suspected genetic modes of transmission are discussed herein, with particular emphasis on cattle. These include: 1. Acrosome defects (knobbed, ruffled and incomplete); 2. Head defects (abnormal condensation, decapitated, round head, rolled head, nuclear crest); 3. Midpiece abnormalities ("Dag" defect, "corkscrew" defect, "pseudo-droplet" defect); 4. Tail defects ("tail stump" defect, primary ciliary dyskinesia).

MeSH terms

  • Acrosome / ultrastructure
  • Animals
  • Cattle
  • Cattle Diseases
  • Environment*
  • Genetic Diseases, Inborn / veterinary*
  • Infertility, Male / etiology
  • Infertility, Male / genetics
  • Infertility, Male / veterinary*
  • Male
  • Sperm Head / ultrastructure
  • Sperm Tail / ultrastructure
  • Spermatozoa / abnormalities*