This research examined well-being in relationship to the variables of hope, spirituality, and state anxiety using a cross-sectional correlation design to test two mediation models. The convenience sample of 130 older adults, mostly women, between the ages of 60 and 89, completed the Demographic Data Sheet and the Index of Well-Being, the Herth Hope Index, the Spiritual Perspective Scale, and the state anxiety portion of the State-Trait Anxiety Inventory. Statistically significant and positive correlations were found between hope and well-being, hope and spirituality, and spirituality and well-being. A statistically significant and negative correlation was found between hope and state anxiety and between state anxiety and well-being. Multiple regression analyses results indicated that neither spirituality nor state anxiety functioned as a mediator in the relationship between hope and well-being.