HIV superinfection

J Infect Dis. 2005 Aug 1;192(3):438-44. doi: 10.1086/431682. Epub 2005 Jun 30.


Worldwide, 16 cases of HIV-1 superinfection in humans have been reported since 2002. Superinfection is defined as the reinfection of an individual who already has an established infection with a heterologous HIV strain. Controversy exists surrounding superinfection, because it has implications concerning our understanding of worldwide HIV diversity, individual immunity and disease progression, and vaccine development. Here, we review the current understanding of HIV superinfection.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • AIDS-Related Opportunistic Infections / classification
  • AIDS-Related Opportunistic Infections / epidemiology*
  • Global Health
  • Humans
  • Superinfection*