Pharmacokinetics of glimepiride and cytochrome P450 2C9 genetic polymorphisms

Clin Pharmacol Ther. 2005 Jul;78(1):90-2. doi: 10.1016/j.clpt.2005.03.008.
No abstract available

Publication types

  • Comment
  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Alleles
  • Area Under Curve
  • Aryl Hydrocarbon Hydroxylases / drug effects
  • Aryl Hydrocarbon Hydroxylases / genetics*
  • Aryl Hydrocarbon Hydroxylases / metabolism
  • Asian Continental Ancestry Group / genetics
  • Cytochrome P-450 CYP2C9
  • Half-Life
  • Heterozygote
  • Humans
  • Liver / drug effects
  • Liver / metabolism
  • Polymorphism, Genetic
  • Sulfonylurea Compounds / administration & dosage
  • Sulfonylurea Compounds / metabolism
  • Sulfonylurea Compounds / pharmacokinetics*

Substances

  • Sulfonylurea Compounds
  • glimepiride
  • CYP2C9 protein, human
  • Cytochrome P-450 CYP2C9
  • Aryl Hydrocarbon Hydroxylases