Chromosome segregation: seeing is believing

Curr Biol. 2005 Jul 12;15(13):R500-3. doi: 10.1016/j.cub.2005.06.033.

Abstract

For chromosome segregation in mitosis, each centromere directs assembly of a complex, proteinaceous structure - the kinetochore, which connects the chromosome to microtubules of the mitotic spindle. A recent study has provided important new insights into the mechanism by which kinetochores capture spindle microtubules.

Publication types

  • Review

MeSH terms

  • Chromosome Segregation / physiology*
  • Kinetochores / metabolism*
  • Metaphase / physiology*
  • Microtubule-Associated Proteins / metabolism
  • Models, Biological*
  • Spindle Apparatus / metabolism*
  • Yeasts

Substances

  • Microtubule-Associated Proteins