C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: efficient lectin inhibition through double arginine-arene interactions

Angew Chem Int Ed Engl. 2005 Aug 12;44(32):5110-2. doi: 10.1002/anie.200500627.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arginine / chemistry*
  • Benzamides / chemistry*
  • Computer Simulation
  • Galectin 3 / antagonists & inhibitors*
  • Models, Chemical
  • Models, Molecular
  • Molecular Structure
  • Structure-Activity Relationship
  • Thiogalactosides / chemistry*

Substances

  • Benzamides
  • Galectin 3
  • Thiogalactosides
  • Arginine