Abstract
A highly enantioselective Michael addition of 1,3-dicarbonyl compounds to nitroalkenes has been developed that employs a newly developed Ni(II)-(bis)diamine based catalyst. The reaction scope includes substituted and unsubstituted malonates, beta-ketoesters, and nitroalkenes bearing aromatic and aliphatic residues. Ease of synthesis of this complex is noteworthy.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Alkenes / chemistry*
-
Catalysis
-
Ketones / chemistry*
-
Nickel / chemistry*
-
Nitro Compounds / chemistry*
-
Organometallic Compounds / chemistry*
-
Stereoisomerism
Substances
-
Alkenes
-
Ketones
-
Ni(II)-bis((R,R)-N,N'-dibenzylcyclohexane-1,2-diamine)Br2
-
Nitro Compounds
-
Organometallic Compounds
-
Nickel