Long-term survival of Parkinson's disease: a population-based study

J Neurol. 2006 Jan;253(1):33-7. doi: 10.1007/s00415-005-0916-7. Epub 2005 Jul 18.


In a set of a population- based study, long-term survival of 59 prevalent PD patients was compared with that of individuals free of neurological diseases matched 1:2 by sex and age of enrolment. PD individuals, compared with reference subjects, showed a two-fold increased risk of death (OR 2.1; 95 % CI 1.4, 3.1). Among causes of death, pneumonia and cachexia were significantly more frequent among PD patients than among individuals free of neurological diseases. We confirmed in a long-term follow-up study an increased mortality among PD individuals compared with that of the general population.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Community Health Planning*
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Parkinson Disease / complications
  • Parkinson Disease / epidemiology*
  • Parkinson Disease / mortality*
  • Proportional Hazards Models
  • Retrospective Studies
  • Risk
  • Risk Factors
  • Sex Factors
  • Survival Analysis
  • Survival Rate