Emergency peripartum hysterectomy: A prospective study in The Netherlands

Eur J Obstet Gynecol Reprod Biol. 2006 Feb 1;124(2):187-92. doi: 10.1016/j.ejogrb.2005.06.012. Epub 2005 Jul 18.


Objective: To determine the incidence, indication, association with caesarean section (CS) and outcome of emergency peripartum hysterectomy (EPH) in The Netherlands.

Study design: All 100 Dutch obstetric departments were asked to participate in a prospective nationwide registration of EPH between 1 April 2002 and 1 April 2003. For every case, a form with questions about obstetrical history, current pregnancy and delivery, maternal and neonatal outcome was completed.

Results: Eighty-nine (89%) hospitals participated and registered in total 48 EPH. The estimated incidence of EPH is 0.33/1000 births. The main indication for EPH was placenta accreta (50%), followed by uterine atony (27%). There were two maternal deaths (4%). Severe maternal morbidity included: urinary tract injury 15%, relaparotomy 25%, transfusion >10 units red blood cells 67%, intensive care admission 77%. Both previous CS and CS in the index pregnancy were associated with a significant increased risk of EPH. The number of previous CS was related to an increased risk of placenta accreta, from 0.19% for one previous CS to 9.1% for four or more previous CS.

Conclusion: Emergency peripartum hysterectomy is associated with a high incidence of maternal morbidity and a case fatality rate of 4%. It is significantly related to CS in index or previous pregnancy. Placenta accreta is the most common indication to perform a peripartum hysterectomy.

MeSH terms

  • Adult
  • Cesarean Section / statistics & numerical data
  • Emergency Treatment / statistics & numerical data*
  • Female
  • Humans
  • Hysterectomy* / statistics & numerical data
  • Incidence
  • Netherlands / epidemiology
  • Obstetric Labor Complications / epidemiology*
  • Obstetric Labor Complications / surgery*
  • Placenta Accreta / epidemiology
  • Placenta Accreta / surgery
  • Postpartum Hemorrhage / epidemiology
  • Postpartum Hemorrhage / surgery
  • Pregnancy
  • Pregnancy Outcome
  • Prospective Studies
  • Risk Factors
  • Uterine Inertia / epidemiology
  • Uterine Inertia / surgery