Vasopressin infusion in children with catecholamine-resistant septic shock

Acta Paediatr. 2005 Mar;94(3):380-3. doi: 10.1111/j.1651-2227.2005.tb03086.x.


Aim: To describe use of vasopressin infusion for catecholamine-refractory septic shock in children.

Methods: We report successful use of vasopressin infusion in three children with septic shock, in whom hypotension and poor perfusion persisted despite use of multiple infusions of vasopressors and inotropes.

Results: All three had a rapid improvement in hypotension and perfusion after starting vasopressin infusion, allowing tapering of other infusions. Two children recovered completely.

Conclusions: Vasopressin appears to be useful in treatment of catecholamine-refractory septic shock in children.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Catecholamines / therapeutic use
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Shock, Septic / physiopathology
  • Treatment Failure
  • Vasoconstrictor Agents / therapeutic use*
  • Vasopressins / therapeutic use*


  • Catecholamines
  • Vasoconstrictor Agents
  • Vasopressins