Acute psychosis after anesthesia: the case for antibiomania

Paediatr Anaesth. 2005 Aug;15(8):703-5. doi: 10.1111/j.1460-9592.2004.01525.x.

Abstract

We report the case of a teenager who developed a postanesthesia acute psychosis (delusions, paranoia, and hallucinations) caused by a reaction to antibiotic therapy (amoxicillin and clarithromycin), so called 'Hoigne's syndrome' or 'antibiomania.' The differential diagnosis and a review of literature are presented. Our patient illustrates the importance of adding antibiomania as part of the differential diagnosis when altered postanesthesia behavior is observed in pediatric patients.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adolescent Behavior / drug effects
  • Amoxicillin / adverse effects*
  • Anesthesia, Inhalation
  • Anesthesia, Intravenous
  • Anti-Bacterial Agents / adverse effects*
  • Cholecystectomy
  • Clarithromycin / adverse effects*
  • Delusions / chemically induced
  • Follow-Up Studies
  • Hallucinations / chemically induced
  • Humans
  • Male
  • Paranoid Behavior / chemically induced
  • Postoperative Complications
  • Psychoses, Substance-Induced / etiology*

Substances

  • Anti-Bacterial Agents
  • Amoxicillin
  • Clarithromycin