Abstract
Various lines of evidence implicate impaired renal function as an important prognostic indicator in patients with congestive heart failure (CHF). Conventional diuretics may aggravate renal dysfunction and can result in neurohumoral activation. Evolving new therapeutic strategies that enhance renal function include administration of B-type natriuretic peptide, adenosine and vasopressin antagonists, and ultrafiltration methods. Prospective studies are needed to evaluate whether these new renal-enhancing strategies will improve patient outcome in CHF.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Biomarkers / analysis
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Combined Modality Therapy
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Comorbidity
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Diet
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Disease Progression
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Diuretics / therapeutic use
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Drug Therapy, Combination
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Female
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Heart Failure / diagnosis
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Heart Failure / epidemiology*
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Heart Failure / therapy*
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Hemofiltration / methods
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Humans
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Kidney Diseases / diagnosis
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Kidney Diseases / epidemiology*
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Kidney Diseases / therapy*
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Kidney Function Tests
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Life Style
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Male
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Prognosis
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Severity of Illness Index
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Survival Rate
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Syndrome