Performance of community-based glaucoma screening using Frequency Doubling Technology and Heidelberg Retinal Tomography

Ophthalmic Epidemiol. 2005 Jun;12(3):167-78. doi: 10.1080/09286580590969716.


Purpose: To assess the performance of a community-based glaucoma screening algorithm in the general population.

Methods: A total of 659 individuals aged 50-90 years were screened for glaucoma. Presenting visual acuity, family history of glaucoma, FDT perimetry, and HRT tests were assessed. Additional samples of participants served as control groups. Participants identified as glaucoma positive received a full ophthalmic examination. Based on this exam a consensus diagnosis was made which served as the gold standard.

Results: The optimal screening strategy combining visual acuity and family history with FDT and HRT had sensitivities, specificities, positive predictive values and negative predictive values of 96.8%, 89.7%, 31.9%, and 99.8% respectively for detecting glaucoma.

Conclusions: By combining assessments of presenting visual acuity and family history of glaucoma with Frequency Doubling Technology perimetry and Heidelberg Retina Tomography, we devised a community glaucoma-screening algorithm that showed a high sensitivity and specificity for detecting glaucoma in the general population.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Algorithms*
  • Chronic Disease
  • Diagnostic Techniques, Ophthalmological*
  • Epidemiologic Studies
  • False Positive Reactions
  • Female
  • Glaucoma / diagnosis*
  • Health Status Indicators
  • Humans
  • Male
  • Mass Screening
  • Middle Aged
  • Optic Nerve Diseases / diagnosis*
  • Predictive Value of Tests
  • Sensitivity and Specificity
  • Systems Integration
  • Tomography
  • Vision Disorders / diagnosis*
  • Visual Acuity
  • Visual Fields