Neural modeling and imaging of the cortical interactions underlying syllable production

Brain Lang. 2006 Mar;96(3):280-301. doi: 10.1016/j.bandl.2005.06.001. Epub 2005 Jul 22.


This paper describes a neural model of speech acquisition and production that accounts for a wide range of acoustic, kinematic, and neuroimaging data concerning the control of speech movements. The model is a neural network whose components correspond to regions of the cerebral cortex and cerebellum, including premotor, motor, auditory, and somatosensory cortical areas. Computer simulations of the model verify its ability to account for compensation to lip and jaw perturbations during speech. Specific anatomical locations of the model's components are estimated, and these estimates are used to simulate fMRI experiments of simple syllable production.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Brain Mapping
  • Cerebral Cortex / physiology
  • Computer Simulation
  • Humans
  • Magnetic Resonance Imaging
  • Models, Neurological
  • Nerve Net / physiology*
  • Psychomotor Performance / physiology
  • Speech / physiology*
  • Synaptic Transmission