Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment

Infect Immun. 2005 Aug;73(8):5278-85. doi: 10.1128/IAI.73.8.5278-5285.2005.

Abstract

Transcriptional profiling of Campylobacter jejuni during colonization of the chick cecum identified 59 genes that were differentially expressed in vivo compared with the genes in vitro. The data suggest that C. jejuni regulates electron transport and central metabolic pathways to alter its physiological state during establishment in the chick cecum.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological*
  • Animals
  • Campylobacter Infections / metabolism*
  • Campylobacter jejuni / genetics*
  • Campylobacter jejuni / metabolism
  • Cecum / microbiology
  • Chickens / microbiology
  • Electron Transport
  • Gene Expression / physiology
  • Gene Expression Profiling
  • Oligonucleotide Array Sequence Analysis
  • Oxygen / metabolism*

Substances

  • Oxygen