Antimicrobial activity of isopteropodine

Rubén García; Cesia Cayunao; Ronny Bocic; Nadine Backhouse; Carle Delporte; Mercedes Zaldivar; Silvia Erazo

doi:10.1515/znc-2005-5-603

Antimicrobial activity of isopteropodine

Z Naturforsch C J Biosci. 2005 May-Jun;60(5-6):385-8. doi: 10.1515/znc-2005-5-603.

Authors

Rubén García¹, Cesia Cayunao, Ronny Bocic, Nadine Backhouse, Carle Delporte, Mercedes Zaldivar, Silvia Erazo

Affiliation

¹ Department of Pharmacological and Toxicological Chemistry, School of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile. rgarciam@uchile.cl

PMID: 16042336
DOI: 10.1515/znc-2005-5-603

Abstract

Bioassay-directed fractionation for the determination of antimicrobial activity of Uncaria tomentosa, has led to the isolation of isopteropodine (0.3%), a known Uncaria pentacyclic oxindol alkaloid that exhibited antibacterial activity against Gram positive bacteria.

MeSH terms

Anti-Infective Agents / chemistry
Anti-Infective Agents / isolation & purification*
Bacteria / drug effects
Gas Chromatography-Mass Spectrometry
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Phytotherapy
Plant Extracts
Plant Stems / chemistry
Saccharomyces cerevisiae / drug effects
Uncaria / chemistry*

Substances

Anti-Infective Agents
Plant Extracts