Thalamic hypofunction in alcohol hallucinosis: FDG PET findings

Psychiatry Res. 2005 Aug 30;139(3):259-62. doi: 10.1016/j.pscychresns.2005.05.009.


We report findings obtained with positron emission tomography with fluorodeoxyglucose-F18 (FDG PET) as tracer in two patients with acute alcohol hallucinosis. In line with previous findings, both patients had a significant hypometabolism in the left relative to the right thalamus. When the second patient was retested after clinical recovery, FDG PET findings were normalized, suggesting the probable thalamic dysfunction to be a functional rather than a structural abnormality.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alcoholism* / complications
  • Alcoholism* / metabolism
  • Alcoholism* / physiopathology
  • Fluorodeoxyglucose F18 / pharmacokinetics*
  • Hallucinations* / etiology
  • Hallucinations* / metabolism
  • Hallucinations* / physiopathology
  • Humans
  • Male
  • Positron-Emission Tomography*
  • Radiopharmaceuticals / pharmacokinetics*
  • Thalamus / metabolism*
  • Thalamus / physiopathology*


  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18