Endocrine manifestations of craniopharyngioma

Abstract

Rationale: Due to the proximity of craniopharyngiomas to the hypothalamus and pituitary gland, most children and adolescents presenting with these tumors will exhibit significant endocrine dysfunction. After treatment, these impairments can become a major cause of morbidity and mortality.

Methods: The postoperative course of children undergoing surgery for craniopharyngioma is reviewed.

Conclusion: Even if hormone levels seem to be adequate in the short term after treatment, deficiencies may develop over years and need to be monitored closely.