Characterization of p30, a Highly Antigenic Membrane and Secreted Protein of African Swine Fever Virus

Virology. 1992 Jul;189(1):368-73. doi: 10.1016/0042-6822(92)90718-5.

Abstract

We have identified and characterized a 30-kDa phosphoprotein (p30) of African Swine Fever Virus (ASFV) that is synthesized, membrane localized, and released into the culture medium at early times after infection. Sequence analysis of the p30 open reading frame predicts a highly antigenic protein with putative phosphorylation, glycosylation, and membrane attachment sites.

MeSH terms

  • African Swine Fever Virus / genetics*
  • African Swine Fever Virus / immunology
  • Amino Acid Sequence
  • Animals
  • Antibodies, Monoclonal
  • Antigens, Viral / biosynthesis
  • Antigens, Viral / genetics*
  • Antigens, Viral / immunology
  • Base Sequence
  • Cells, Cultured
  • Glycosylation
  • Macrophages / microbiology
  • Membrane Proteins / genetics
  • Membrane Proteins / immunology
  • Membrane Proteins / metabolism
  • Molecular Sequence Data
  • Phosphoproteins / genetics*
  • Phosphoproteins / immunology
  • Phosphoproteins / metabolism
  • Phosphorylation
  • Protein Conformation
  • Swine
  • Viral Proteins / genetics*
  • Viral Proteins / immunology
  • Viral Proteins / metabolism

Substances

  • Antibodies, Monoclonal
  • Antigens, Viral
  • Membrane Proteins
  • Phosphoproteins
  • Viral Proteins
  • P30 protein, African Swine Fever Virus

Associated data

  • GENBANK/M88336