Predictors of exercise capacity and everyday activity in older heart failure patients

Eur J Heart Fail. 2006 Mar;8(2):203-7. doi: 10.1016/j.ejheart.2005.03.008. Epub 2005 Jul 25.


Background: Exercise capacity and daily activity are key outcomes for older, frail heart failure patients. Little is known about the determinants of these outcomes in this patient group.

Aims: To explore predictors of exercise capacity and daily activity in older, frail heart failure patients.

Methods: Analysis of prospectively collected data from a cohort of 82 patients aged 70 years and over, enrolled in a randomised controlled trial of exercise in heart failure patients. Pathophysiological, demographic, psychological and social factors were analysed by multivariate regression to determine predictors of exercise capacity (6-min walk distance) and daily activity (daily accelerometer counts).

Results: Between 49% and 55% of the variance in 6-min walk distance was explained by variables including New York Heart Association class, depression score, attitude to ageing and use of walking aids. Only 11% to 26% of the variance in accelerometer scores was explained by the model; 6-min walk distance was the only consistent predictor of daily activity.

Conclusions: Physical, psychological and attitudinal variables contribute to variance of the 6-min walk. Six-minute walk distance predicts a small amount of the variance in daily activity, but the majority of variance in daily activity remains unexplained and requires further investigation.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living*
  • Aged
  • Aged, 80 and over
  • Chronic Disease
  • Cohort Studies
  • Exercise Test / methods
  • Exercise Tolerance*
  • Female
  • Heart Failure / physiopathology*
  • Humans
  • Male
  • Prospective Studies