[The relationship between microalbuminuria and plasma high sensitivity C reactive protein]

Zhonghua Xin Xue Guan Bing Za Zhi. 2005 Jun;33(6):534-5.
[Article in Chinese]

Abstract

Objective: To investigate the relationship between microalbuminuria (MA) and plasma high sensitivity C reactive protein (hsCRP).

Method: The plasma hsCRP level and urine albumin level of 746 Chinese people were detected with ELISA and analyzed, respectively.

Result: The hsCRP level of MA group increased significantly compared with the control group (2.23 +/- 3.35 mg/L vs 1.68 +/- 2.58 mg/L, P < 0.05), the incidence of MA increased significantly when the plasma hsCRP level was beyond 0.77 mg/L (P < 0.05); logistic analysis showed that the occurrence of MA was associated with the plasma hsCRP level (OR = 1.153, P < 0.05).

Conclusion: Increased plasma hsCRP was probably involved in the occurrence of MA, suggesting that inflammation may deteriorate endothelial dysfunction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Albuminuria / urine*
  • Asian People
  • C-Reactive Protein / analysis*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Inflammation*
  • Male
  • Middle Aged

Substances

  • C-Reactive Protein