An actin fishnet for DNA

Nat Cell Biol. 2005 Aug;7(8):775-6. doi: 10.1038/ncb0805-775.

Abstract

It has long been thought that gathering chromosomes during spindle assembly is exclusively the responsibility of microtubules. However, a recent study by Lénárt et al. shows that, in larger cells, a collapsing network of actin filaments ensnares and transports the chromosomes, bringing them in range for microtubule capture.

Publication types

  • News

MeSH terms

  • Actins / physiology*
  • Animals
  • Cell Division / physiology
  • Chromosomes / physiology*
  • Female
  • Meiosis / physiology
  • Microtubules / physiology
  • Models, Biological
  • Oocytes / physiology
  • Spindle Apparatus / physiology*
  • Starfish

Substances

  • Actins