Systematic review of economic evaluations of smoking cessation: standardizing the cost-effectiveness

Med Decis Making. 2005 Jul-Aug;25(4):437-48. doi: 10.1177/0272989X05278431.


Objectives: This study was performed to render cost-effectiveness studies on smoking cessation therapies, utilized until now, more comparable and more useful for medical decision making.

Methods: The cost-effectiveness ratios reported by the studies were recalculated using a societal perspective and guidelines for economic evaluation.

Results: The costs of individual interventions generally increased as a result of the standardization procedure, whereas the effect size decreased. This resulted in increases in the cost-effectiveness ratios for individual studies ranging from 120% to 5600%.

Conclusions: The variation between studies in the percentage increase in cost-effectiveness ratios is huge. This means that not following guidelines when calculating cost-effectiveness ratios can result in large errors. Despite the fact that the standardized cost-effectiveness ratios of smoking interventions were higher than the unstandardized cost-effectiveness ratios, interventions aimed at reducing the prevalence of smoking are cost-effective.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Cost-Benefit Analysis*
  • Guidelines as Topic
  • Humans
  • Smoking Cessation / economics*