Decreased bacterial adherence to silver-coated stent material: an in vitro study

Gastrointest Endosc. 1992 May-Jun;38(3):338-40. doi: 10.1016/s0016-5107(92)70428-3.


Bacteria are important in causing biliary stent blockage through adherence and subsequent biofilm formation. In our in vitro system, surface modification using test polyurethane discs with silver coating led to a reduction in the number of adherent bacteria compared with untreated controls by 10- to 100-fold in an apparently dose-related manner. The effect was more marked in the presence of bile. These results suggest that silver coating may have a potential benefit in preventing stent blockage.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Adhesion*
  • Bile
  • Escherichia coli / physiology
  • Humans
  • In Vitro Techniques
  • Microscopy, Electron, Scanning
  • Polyurethanes
  • Silver*
  • Stents*
  • Surface Properties


  • Polyurethanes
  • Silver