Pulmonary vascular manifestations of mixed connective tissue disease

Rheum Dis Clin North Am. 2005 Aug;31(3):451-64, vi. doi: 10.1016/j.rdc.2005.04.010.


Mixed connective tissue disease (MCTD) refers to a disease process with combined clinical features characteristic of systemic lupus erythematous, scleroderma, and polymyositis-dermatomyositis. This article focuses on the pulmonary vasculature manifestations of MCTD. We briefly discuss associations between MCTD and interstitial lung disease, pleural disease, and alveolar hemorrhage.

Publication types

  • Review

MeSH terms

  • Humans
  • Hypertension, Pulmonary / drug therapy
  • Hypertension, Pulmonary / etiology*
  • Hypertension, Pulmonary / physiopathology
  • Lung Diseases, Interstitial / etiology
  • Mixed Connective Tissue Disease / complications*
  • Mixed Connective Tissue Disease / physiopathology
  • Pleural Diseases / etiology
  • Pulmonary Alveoli
  • Pulmonary Circulation / physiology