Diagnosis and management of human parvovirus B19 infection

Clin Perinatol. 2005 Sep;32(3):697-704. doi: 10.1016/j.clp.2005.04.003.


Parvovirus B19 is a common infection in children occurring in winter and spring months that can affect pregnant women and their unborn fetuses. Adverse fetal sequelae may include red blood cell aplasia due to bone marrow suppression, anemia, myocarditis, nonimmune hydrops, and fetal death. Fortunately, several noninvasive testing schemes are available to assess the fetus, and invasive testing is reserved for fetuses with marked anemia.

Publication types

  • Review

MeSH terms

  • Antibodies, Viral / analysis
  • DNA, Viral / analysis
  • Female
  • Humans
  • Parvoviridae Infections* / diagnosis
  • Parvoviridae Infections* / therapy
  • Parvovirus B19, Human / genetics*
  • Parvovirus B19, Human / immunology
  • Pregnancy
  • Pregnancy Complications, Infectious* / diagnosis
  • Pregnancy Complications, Infectious* / therapy
  • Prenatal Care / methods*
  • Prenatal Diagnosis / methods*
  • Time Factors


  • Antibodies, Viral
  • DNA, Viral