Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
, 10 (4), 277-9

Cytomegalovirus-induced Thrombocytopenia in an Immunocompetent Adult Effectively Treated With Intravenous Immunoglobulin: A Case Report and Review

Affiliations
Case Reports

Cytomegalovirus-induced Thrombocytopenia in an Immunocompetent Adult Effectively Treated With Intravenous Immunoglobulin: A Case Report and Review

Carol Alliot et al. Hematology.

Abstract

The authors report the case of an 80-year-old male patient who presented with colitis and severe thrombocytopenia. The work-up revealed concurrent cytomegalovirus infection. After failure of prednisone, a single infusion of high-dose intravenous immunoglobulin produced a rapid and sustained response. Seventeen cases from the world literature are reviewed. Corticosteroids seem effective in about one third of cases. In those who do not respond, splenectomy is relatively ineffective and more specific anti-CMV treatment with ganciclovir is of unproven efficacy and toxic, in view of the relatively favourable long term outcome the authors recommend intravenous immunoglobulin in cases of severe bleeding or when the platelet level is under 10 x 10(9) l.

Similar articles

See all similar articles

Cited by 1 article

Publication types

MeSH terms

LinkOut - more resources

Feedback