Reverse transcription in genome evolution

Cytogenet Genome Res. 2005;110(1-4):56-62. doi: 10.1159/000084938.


As reverse transcription is predominantly performed by retrotransposable elements, the process is often entirely associated with the propagation of these elements. However, as a unique tool for transmitting information from the dynamic RNA to the more inert DNA, reverse transcription has been instrumental in shaping extant genomes. This review aims at presenting the diversity by which reverse transcription has influenced modern genomic structures.

Publication types

  • Review

MeSH terms

  • Animals
  • Evolution, Molecular*
  • Genome*
  • Humans
  • Retroelements
  • Reverse Transcription / genetics*
  • Transcription, Genetic


  • Retroelements