Identification of occupational cancer risks in British Columbia: a population-based case-control study of 1129 cases of bladder cancer

J Occup Environ Med. 2005 Aug;47(8):854-8. doi: 10.1097/01.jom.0000169094.77036.1d.


Objective: We collected information on lifetime occupational histories, smoking, and alcohol consumption from 15,463 incident cancer cases. Occupational risk factors for bladder cancer are presented in this report.

Method: A matched case-control design was used. All cases were diagnosed with bladder cancers, with controls being internal controls consisting of all other cancer sites, excluding lung and unknown primary. Data were analyzed using conditional logistic regression for matched sets data and the likelihood ratio test.

Results: Excess bladder cancer risks was observed in a number of occupation and industries, particularly those involving exposure to metals, including aluminum, paint and solvents, polycyclic aromatic hydrocarbons, diesel engine emissions, and textiles.

Conclusions: The results of our study are in line with those from the literature and further suggest that exposure to silica and to electromagnetic fields may carry an increased risk of bladder cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • British Columbia / epidemiology
  • Case-Control Studies
  • Humans
  • Industry / classification*
  • Industry / statistics & numerical data
  • Logistic Models
  • Male
  • Metals / adverse effects
  • Middle Aged
  • Occupational Diseases / epidemiology*
  • Occupational Diseases / etiology
  • Occupational Exposure / adverse effects*
  • Occupational Exposure / analysis
  • Occupational Exposure / classification
  • Occupations / classification
  • Paint / adverse effects
  • Registries
  • Risk Factors
  • Solvents / adverse effects
  • Surveys and Questionnaires
  • Textiles / adverse effects
  • Urinary Bladder Neoplasms / epidemiology*
  • Urinary Bladder Neoplasms / etiology
  • Vehicle Emissions / adverse effects
  • Workforce


  • Metals
  • Solvents
  • Vehicle Emissions