The authors investigated the relationships among stress, values, and value conflict. Data collected from 400 people working in a variety of companies in Flanders indicated that the values of openness to change, conservation, self-transcendence, and self-enhancement were important predictors of stress. Participants open to change reported less stress, whereas participants who had high scores on conservation, self-enhancement, and self-transcendence perceived more stress. People who reported high value conflict also experienced more stress. Separate analyses for men and women showed that there were gender differences in the relationships observed between the 4 value types and stress. These data have noteworthy theoretical and practical implications.