Abstract
Using the iron-mediated arylamine cyclization as the key step we have achieved a short and highly efficient access to the biologically active 2,7-dioxygenated tricyclic carbazole alkaloids 7-methoxy-O-methylmukonal, clausine H (clauszoline-C), clausine K (clauszoline-J) and clausine O.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemical synthesis*
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Carbazoles / chemical synthesis*
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Crystallography, X-Ray
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Cyclization
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Heterocyclic Compounds, 3-Ring / chemical synthesis*
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Iron / chemistry
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Models, Molecular
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Molecular Structure
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Organometallic Compounds / chemical synthesis
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Organometallic Compounds / chemistry*
Substances
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7-methoxy-O-methylmukonal
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Alkaloids
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Carbazoles
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Heterocyclic Compounds, 3-Ring
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Organometallic Compounds
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clausine H
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clausine O
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Iron