Abstract
An Aurora A regulatory module has been identified in two different proteins: TPX2 in Xenopus laevis and TPXL-1 in C. elegans. The diverse roles of these two proteins in spindle assembly leave us to beckon the true C. elegans TPX2 ortholog to center stage.
MeSH terms
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Animals
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Aurora Kinases
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Caenorhabditis elegans Proteins / genetics
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Caenorhabditis elegans Proteins / physiology*
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Cell Cycle Proteins / genetics
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Cell Cycle Proteins / physiology*
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Microtubule-Associated Proteins / genetics
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Microtubule-Associated Proteins / physiology*
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Neoplasm Proteins / genetics
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Neoplasm Proteins / physiology*
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Nuclear Proteins / genetics
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Nuclear Proteins / physiology*
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Phosphoproteins / genetics
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Phosphoproteins / physiology*
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Protein Serine-Threonine Kinases / genetics
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Protein Serine-Threonine Kinases / physiology*
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Sequence Homology
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Xenopus Proteins / genetics
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Xenopus Proteins / physiology*
Substances
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Caenorhabditis elegans Proteins
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Cell Cycle Proteins
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Microtubule-Associated Proteins
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Neoplasm Proteins
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Nuclear Proteins
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Phosphoproteins
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TPX2 protein, Xenopus
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Xenopus Proteins
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Aurora Kinases
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Protein Serine-Threonine Kinases