TPX or not TPX?

Mol Cell. 2005 Aug 19;19(4):431-2. doi: 10.1016/j.molcel.2005.08.002.

Abstract

An Aurora A regulatory module has been identified in two different proteins: TPX2 in Xenopus laevis and TPXL-1 in C. elegans. The diverse roles of these two proteins in spindle assembly leave us to beckon the true C. elegans TPX2 ortholog to center stage.

Publication types

  • Review

MeSH terms

  • Animals
  • Aurora Kinases
  • Caenorhabditis elegans Proteins / genetics
  • Caenorhabditis elegans Proteins / physiology*
  • Cell Cycle Proteins / genetics
  • Cell Cycle Proteins / physiology*
  • Microtubule-Associated Proteins / genetics
  • Microtubule-Associated Proteins / physiology*
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / physiology*
  • Nuclear Proteins / genetics
  • Nuclear Proteins / physiology*
  • Phosphoproteins / genetics
  • Phosphoproteins / physiology*
  • Protein-Serine-Threonine Kinases / genetics
  • Protein-Serine-Threonine Kinases / physiology*
  • Sequence Homology
  • Xenopus Proteins / genetics
  • Xenopus Proteins / physiology*

Substances

  • Caenorhabditis elegans Proteins
  • Cell Cycle Proteins
  • Microtubule-Associated Proteins
  • Neoplasm Proteins
  • Nuclear Proteins
  • Phosphoproteins
  • TPX2 protein, Xenopus
  • Xenopus Proteins
  • Aurora Kinases
  • Protein-Serine-Threonine Kinases