Consensus recommendations of the Italian Association for Neuroimmunology for immunochemical cerebrospinal fluid examination

J Neurol Sci. 2005 Oct 15;237(1-2):5-11. doi: 10.1016/j.jns.2005.07.002.


In 2002-2003, the Italian Association for Neuroimmunology (AINI) ran a program for procedure and method standardization in neuroimmunology. The main purposes of the program were: a) to improve the overall quality of analytical performance and, simultaneously, to reduce costs by resource optimization; b) to establish the bases for clinical guidelines in neurology; c) to promote the formation of laboratory networks and of joint research projects; d) to facilitate the procedures for certification required by governmental/non-governmental agencies. This report summarizes the consensus recommendations of a panel of AINI neuroimmunologists/biochemists involved in the field of cerebrospinal fluid examination. The collection process for said recommendations was guided by "impact-factored" literature and the knowledge of the experts involved. Communication was by email and face-to-face at two dedicated AINI workshops.

Publication types

  • Consensus Development Conference
  • Guideline
  • Review

MeSH terms

  • Animals
  • Antibodies / cerebrospinal fluid
  • Antigens / cerebrospinal fluid
  • Cerebrospinal Fluid / chemistry*
  • Cerebrospinal Fluid / cytology*
  • Cerebrospinal Fluid / immunology
  • Humans
  • Immunochemistry / standards*
  • Immunoglobulin G / cerebrospinal fluid
  • Neurology / standards*


  • Antibodies
  • Antigens
  • Immunoglobulin G