The Tajimi Study report 2: prevalence of primary angle closure and secondary glaucoma in a Japanese population

Ophthalmology. 2005 Oct;112(10):1661-9. doi: 10.1016/j.ophtha.2005.05.012.


Purpose: To determine the prevalence of primary angle-closure glaucoma (PACG), secondary glaucoma (SG), and all glaucoma in a Japanese population as a part of the Tajimi Study.

Design: Population-based epidemiological survey.

Participants: A random sample of residents 40 years or older from Tajimi, Japan.

Intervention: Each subject underwent a screening program comprising an interview and an ophthalmic examination, including Goldmann applanation tonometry, slit-lamp examination, a van Herick test, fundus photography, and a screening visual field (VF) test using frequency-doubling technology. If glaucoma was suspected, the subject was referred for a definitive examination that included slit-lamp examination, gonioscopy, intraocular pressure measurement, a VF test, and optic disc and fundus examination. A diagnosis of PACG or SG was made based on slit-lamp examination, gonioscopy, optic disc appearance, and perimetric results.

Main outcome measures: Prevalences of PACG, SG, and all cases of glaucoma.

Results: Of 3870 eligible people, 3021 (78.1%) participated in the study. Estimated prevalences of PACG and SG in those over 40 years were 0.6% (95% confidence interval [CI], 0.4%-0.9%) and 0.5% (95% CI, 0.2%-0.7%), respectively. Prevalences of all glaucoma and glaucoma/suspected glaucoma were estimated to be 5.0% (95% CI, 4.2%-5.8%) and 7.5% (95% CI, 6.5%-8.4%), respectively.

Conclusions: Prevalences were 0.6%, 0.5%, and 5.0%, respectively, for PACG, SG, and all glaucoma in subjects over 40 years from Tajimi, Japan.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Female
  • Glaucoma / diagnosis
  • Glaucoma / epidemiology
  • Glaucoma / etiology
  • Glaucoma, Angle-Closure / diagnosis
  • Glaucoma, Angle-Closure / epidemiology*
  • Gonioscopy
  • Humans
  • Intraocular Pressure
  • Japan / epidemiology
  • Male
  • Middle Aged
  • Nerve Fibers / pathology
  • Optic Disk / pathology
  • Optic Nerve Diseases / diagnosis
  • Prevalence
  • Sex Distribution
  • Tonometry, Ocular
  • Visual Fields