Prospective study of the clinical impact of EUS

Gastrointest Endosc. 2005 Sep;62(3):399-405. doi: 10.1016/s0016-5107(05)01631-7.


Background: Studies on the clinical impact of EUS are lacking. The aim of this study was to examine the impact of EUS on the management plans by referring doctors and patient outcomes.

Methods: Consecutive patients undergoing EUS between August 2002 and June 2004 were prospectively studied. Referring doctors were given a pre-EUS questionnaire that asked about provisional diagnosis and management plan. A post-EUS questionnaire was sent 6 weeks after the procedure.

Results: A total of 330 patients were examined, and completed questionnaires were received in 70%. EUS-guided FNA was performed in 69 (30%) patients. EUS resulted in a change in diagnosis and management in 26% and 48% of cases, respectively. Thirty-nine of the latter patients (33%) avoided unnecessary surgery. In 50% of cases, additional investigations were avoided. Doctors reported EUS as very or moderately useful in 210 patients (91%). Doctors of 223 patients (97%) reported that they would use EUS again.

Conclusions: The use of EUS had a significant clinical impact on patients. EUS resulted in a change of diagnosis in a fourth of patients and a change in management in half of patients studied.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Fine-Needle
  • Chi-Square Distribution
  • Diagnosis, Differential
  • Digestive System Neoplasms / diagnostic imaging*
  • Digestive System Neoplasms / pathology
  • Endosonography / methods*
  • Female
  • Humans
  • Immunohistochemistry
  • Lymph Nodes / pathology*
  • Male
  • Mediastinal Neoplasms / diagnostic imaging*
  • Mediastinal Neoplasms / pathology
  • Middle Aged
  • Neoplasm Invasiveness / diagnostic imaging*
  • Neoplasm Invasiveness / pathology
  • Probability
  • Prospective Studies
  • Referral and Consultation
  • Risk Assessment
  • Sensitivity and Specificity