Cervical clear cell meningioma mimicking a vertebral metastasis

J Clin Neurosci. 2005 Aug;12(6):685-7. doi: 10.1016/j.jocn.2004.08.019.


Cervical vertebral involvement of clear cell meningioma is very rare. We report a case of clear cell meningioma in the cervical vertebral body in a 72-year old male. Seven years prior to this presentation, the patient underwent palliative surgery and posterior instrumentation for a cervical vertebral tumor at C5, which had been diagnosed as a metastatic renal cell carcinoma. On this admission, the patient presented with severe neck pain. Examination revealed hypesthesia on the left in a C6 nerve root distribution. Plain X-rays and MRI revealed an enlarging tumor in the C5 and C6 vertebral bodies. The tumor was resected via an anterior approach followed by fusion using a strut bone graft. Histological examination of the surgical specimen diagnosed a clear cell meningioma. Postoperatively, the patient achieved pain relief and resolution of the neurological deficit. At follow-up two years postoperatively, he remains asymptomatic. We emphasize that cervical clear cell meningioma with involvement of the vertebral bodies may mimic metastatic renal cell carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Renal Cell / secondary*
  • Cervical Vertebrae / pathology*
  • Cervical Vertebrae / surgery
  • Decompression, Surgical
  • Humans
  • Kidney Neoplasms / secondary*
  • Magnetic Resonance Imaging / methods
  • Male
  • Meningeal Neoplasms / pathology*
  • Meningeal Neoplasms / surgery
  • Meningioma / pathology*
  • Meningioma / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome