Patients at risk of onychomycosis--risk factor identification and active prevention

J Eur Acad Dermatol Venereol. 2005 Sep;19 Suppl 1:13-6. doi: 10.1111/j.1468-3083.2005.01282.x.


Objectives: The aims of this workshop were to identify risk factors for onychomycosis and to reach consensus on the management of high-risk groups to allow the development of guidelines to help doctors recognize risk factors that complicate treatment.

Results and conclusions: Previous Trichophyton rubrum infection, older age, abnormal nail morphology, immunodeficiency and genetic factors were identified as risk factors for initial infections. Risk factors for recurrence (relapse and re-infection) are largely the same. The experts agreed that the prevention of onychomycosis and its recurrence should be based on the correct treatment of tinea pedis, screening family members and adequate patient education. In addition, generic management recommendations for each high-risk group were discussed: * Immunosuppressed patients Usual dose and treatment length not appropriate Follow-up required Beware of drug interactions * Diabetics Prophylactic foot care combined with nail treatment Good opportunity for patient education, footwear, foot care, etc. Beware of drug interactions * Psoriatics and patients with abnormal nails Dermatophyte eradication does not restore normal nails * Children High failure rate possibly due to compliance problems.

Publication types

  • Comparative Study
  • Consensus Development Conference

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Antifungal Agents / therapeutic use
  • Child
  • Female
  • Follow-Up Studies
  • Humans
  • Hygiene
  • Incidence
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Onychomycosis / diagnosis
  • Onychomycosis / epidemiology*
  • Onychomycosis / prevention & control*
  • Primary Prevention / methods*
  • Risk Factors
  • Secondary Prevention
  • Severity of Illness Index
  • Sex Distribution


  • Antifungal Agents