Side effects of dextromethorphan abuse, a case series

Addict Behav. 2005 Sep;30(8):1607-13. doi: 10.1016/j.addbeh.2005.02.005.


The aim of this study was to investigate the Dextromethorphan (DXM) abuse side effects. Subjects were 53 volunteers who had consumed DXM with mean age 23.4 years. The mean of side effects during first day was 12.49 and during first week was 5.57. The causes of repeated DXM abuse were psychological dependency 46.5%, recreational abuse in 32.6%. Neurological and psychological symptoms were the most common of side effects in DXM abusers.

MeSH terms

  • Adolescent
  • Adult
  • Analgesics, Opioid / adverse effects*
  • Dextromethorphan / adverse effects*
  • Female
  • Gastrointestinal Diseases / chemically induced
  • Humans
  • Male
  • Mental Disorders / chemically induced
  • Nervous System Diseases / chemically induced
  • Opioid-Related Disorders / complications*
  • Opioid-Related Disorders / psychology


  • Analgesics, Opioid
  • Dextromethorphan