Global epidemiology of hepatitis C virus infection

Lancet Infect Dis. 2005 Sep;5(9):558-67. doi: 10.1016/S1473-3099(05)70216-4.

Abstract

Hepatitis C virus (HCV) is a major cause of liver disease worldwide and a potential cause of substantial morbidity and mortality in the future. The complexity and uncertainty related to the geographic distribution of HCV infection and chronic hepatitis C, determination of its associated risk factors, and evaluation of cofactors that accelerate its progression, underscore the difficulties in global prevention and control of HCV. Because there is no vaccine and no post-exposure prophylaxis for HCV, the focus of primary prevention efforts should be safer blood supply in the developing world, safe injection practices in health care and other settings, and decreasing the number of people who initiate injection drug use.

Publication types

  • Review

MeSH terms

  • Blood Transfusion / standards
  • Cross Infection / prevention & control
  • Global Health*
  • HIV Infections / epidemiology
  • HIV Infections / prevention & control
  • HIV Infections / transmission
  • Hepatitis C / epidemiology*
  • Hepatitis C / prevention & control*
  • Hepatitis C / transmission
  • Hepatitis C, Chronic / epidemiology
  • Hepatitis C, Chronic / prevention & control
  • Hepatitis C, Chronic / transmission
  • Humans
  • Needle-Exchange Programs
  • Risk Factors
  • Substance Abuse, Intravenous / virology