Hypergravity and aging in Drosophila melanogaster. 4. Climbing activity

Gerontology. 1992;38(1-2):59-64. doi: 10.1159/000213307.


Drosophila melanogaster flies climb up the sides of their vial after having been submitted to a mechanical stimulation; that ability is impaired at older ages. The climbing activity (CLI) of flies kept at various gravity levels (1, 3 and 5 g) has been measured throughout life, in cross-sectional studies. Hypergravity had no effect on CLI at young age, but older flies kept in hypergravity displayed lower scores than flies kept at 1 g. Results are discussed in relation with the hypothesis of increased aging rate in hypergravity.

MeSH terms

  • Aging / physiology*
  • Animals
  • Drosophila melanogaster / physiology*
  • Female
  • Gravitation*
  • Locomotion / physiology
  • Male
  • Motor Activity / physiology