Biochemical markers for the prediction of preterm labor

Obstet Gynecol Clin North Am. 2005 Sep;32(3):369-81. doi: 10.1016/j.ogc.2005.04.002.

Abstract

Premature labor and subsequent premature delivery is the major cause of perinatal death in the world. Numerous risk factors identify patients at jeopardy for preterm labor, but with poor sensitivity. Several biologic and biochemical markers have been recently studied that may allow early identification of patients at risk of preterm delivery. Although two markers have received Food and Drug Administration approval, a number of other tests also may ultimately prove useful.

Publication types

  • Review

MeSH terms

  • Biomarkers / metabolism*
  • Chorionic Gonadotropin, beta Subunit, Human / metabolism
  • Corticotropin-Releasing Hormone / metabolism
  • Estriol / metabolism
  • Female
  • Fibronectins / metabolism
  • Glycoproteins / metabolism
  • Humans
  • Obstetric Labor, Premature / diagnosis*
  • Obstetric Labor, Premature / prevention & control
  • Pregnancy
  • Sensitivity and Specificity
  • alpha-Fetoproteins / metabolism

Substances

  • Biomarkers
  • Chorionic Gonadotropin, beta Subunit, Human
  • FFN protein, human
  • Fibronectins
  • Glycoproteins
  • alpha-Fetoproteins
  • Corticotropin-Releasing Hormone
  • Estriol