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, 12 (8), 862-4

Indirect Detection of DNA Damage


Indirect Detection of DNA Damage

L James Maher 3rd. Chem Biol.


In this issue of Chemistry and Biology, Naegeli and coworkers show that the nucleotide excision repair system of mammalian cells detects bulky DNA adducts, not by recognition of the adduct per se, but by recognition of the undamaged partner strand in bulged form.

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