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, 12 (8), 862-4

Indirect Detection of DNA Damage

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Indirect Detection of DNA Damage

L James Maher 3rd. Chem Biol.

Abstract

In this issue of Chemistry and Biology, Naegeli and coworkers show that the nucleotide excision repair system of mammalian cells detects bulky DNA adducts, not by recognition of the adduct per se, but by recognition of the undamaged partner strand in bulged form.

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