Ivermectin 20 years on: maturation of a wonder drug

Trends Parasitol. 2005 Nov;21(11):530-2. doi: 10.1016/j.pt.2005.08.014. Epub 2005 Aug 26.


Ivermectin has been on the veterinary market for almost a quarter of a century and has been approved for human use for 18 years. Its use has revolutionized the treatment of nematode and arthropod parasites in animals and has provided hope for the control or even eradication of filariases in humans. Although much remains to be learned about how the drug works and how resistance to it will develop, it has earned the title of "wonder drug".

Publication types

  • Review

MeSH terms

  • Animals
  • Antiparasitic Agents / pharmacology
  • Antiparasitic Agents / therapeutic use
  • Drug Resistance
  • Forecasting
  • Humans
  • Insecticides / pharmacology
  • Insecticides / therapeutic use
  • Ivermectin* / pharmacology
  • Ivermectin* / therapeutic use
  • Technology, Pharmaceutical / trends


  • Antiparasitic Agents
  • Insecticides
  • Ivermectin